Trueself® Skin Innovation Experience:
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Provides immediate facial volume restoration and precise contouring. CaHa maintains its shape without attracting water, unlike conventional HA fillers. New third-generation safe CaHa particles actively stimulate fibroblasts, promoting collagen and elastin synthesis for natural and long-lasting tissue regeneration. With the new MESO-TRUESELF® technique, we have taken rejuvenation to a whole new level.
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TRUESELF® 400 PLLA stimulates fibroblasts with a new, advanced polarized third-generation molecule, promoting neocollagenesis for firmer and more elastic skin. We have fully redesigned the formula to enhance effectiveness. Safe, uniform 20–30 µm particles ensure even distribution and long-lasting tissue remodeling. Controlled, natural skin rejuvenation for a refined, natural effect—without adding volume. Are you into biotechnology? Join the TRUESELF® family!
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Experience 12–18 months of progressive improvement, as your body actively generates new collagen for lasting skin rejuvenation.
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Produced under CE- and ISO-aligned quality systems, supporting biocompatibility, safety, and reliable bioresorption profiles.
Trueself® 2026 NEW Family:
Professional Skin Rejuvenation Formula • Advanced skin regeneration.
A next-generation skin booster designed to improve skin quality through deep hydration and biological regeneration.
• Improved skin texture & elasticity
• Enhanced luminosity
• Progressive revitalization
• Natural, refreshed appearance
TRUESELF® PLLA 400 — Next-Generation Poly-L-Lactic Acid
Natural youth restoration with a unique 3rd-generation Poly-L-Lactic Acid molecule (20–30 µm)
Starting in 2025, we fully redesigned the architecture of the TRUESELF® PLLA formula and particles: transitioning from 7–10 µm to 20–30 µm particles delivers enhanced collagen stimulation and longer-lasting biostimulation while maintaining a high safety profile.
Enhanced 2025 formula — for more pronounced, predictable results and visible rejuvenation at any age.
Intensive regeneration for delicate areas, including post-device treatment recovery.
TRUESELF® Skin Repair contains a highly concentrated PDRN complex of three types combined with a patented molecular formula, triggering rapid and predictable collagen stimulation at the cellular level. The effect of device-based procedures is synergistically enhanced. When combined with fractional CO₂ or other laser treatments, microneedling RF, HIFU, and other device-based therapies, it delivers maximal results, including faster recovery and superior overall efficacy.
Trueself CaHa® is a next-generation professional product designed for lifting and restoring lost volume while simultaneously stimulating the natural production of collagen and elastin. It features the patented Advanced Microsphere Architecture® technology, ensuring safe and uniform distribution of high-density calcium hydroxyapatite microspheres, providing stable tissue support and natural facial contours.
The new molecule and optimized microsphere porosity enhance biocompatibility and prolong the effect, delivering a natural, harmonious result with long-lasting action.
Trueself CaHa® stands out from other hydroxyapatites due to its high concentration, unique particle design, and controlled tissue integration, making it a safe and predictable tool for professional aesthetic rejuvenation procedures.
Technology
Precision Particle Calibration
The key to safety and efficacy is PLLA molecule size. Optimal range is 20–30 micrometers.
Ineffective for collagen stimulation
Ideal results without side effects
Higher complication risk
Why Particle Size Matters
The particle size of Poly-L-Lactic Acid (PLLA) plays a decisive role in biostimulatory efficacy, duration of clinical results, and overall safety profile.
Small Particles(5–20 µm)
Particles of small diameter are rapidly recognized and phagocytosed by macrophages.
- Short dermal residence time
- Limited fibroblast activation
- Weak collagen stimulation
Only mild and temporary effects requiring frequent retreatment.
Optimal Range(20–30 µm)
Scientifically engineered for maximum efficacy.
- Stable dermal anchoring
- Controlled fibroblast activation
- Uniform neocollagenesis
- Minimal risk of nodules
Large Particles(30–60 µm+)
Larger particles possess increased mass and aggregation tendency.
- Uneven tissue distribution
- Local dermal conglomerates
- Elevated nodule risk
- Reduced predictability
TRUESELF® PLLA — The Clinically Optimal Range
TRUESELF® PLLA is engineered with strictly controlled particles sized 20–30 µm, widely regarded as the optimal range for injectable biostimulation.
This size ensures:
- Stable dermal anchoring without inflammatory aggregation
- Controlled fibroblast activation for predictable results
- Uniform neocollagenesis without excessive inflammatory response
- Minimal risk of aggregation and nodular formation
- Particle polarization for homogeneous tissue distribution
The result: a stable biostimulatory matrix with reproducible, physiological outcomes.
Precision-engineered for safety, efficacy, and natural-looking results.
Why TRUESELF® PLLA?
The Golden Balance
Why TRUESELF® PLLA stands apart in biostimulation efficacy and safety
KEY ADVANTAGE OF TRUESELF® PLLA
TRUESELF® PLLA represents the golden balance between efficacy and safety:
- More pronounced and long-lasting results compared to fine-particle formulations
- Significantly higher safety profile than large-particle PLLA products
- Physiological, long-term collagen stimulation without compromise
- Improved skin texture and natural rejuvenation
The result is superior outcomes with predictable, reproducible clinical success.
Indications
Facial Volume Restoration
Restores lost volume in temples and cheeks for a natural, lifted look.
Correction of Facial Wrinkles and Folds
Smooths deep nasolabial folds and marionette lines effectively.
Body Volume Enhancement and Contouring
Non-surgical shaping for hips, buttocks, and décolletage areas.
Skin Firming and Texture Improvement
Boosts collagen to tighten skin, reduce pores, and improve elasticity.
FAQs
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PLLA (Poly-L-Lactic Acid) is a biocompatible, biodegradable synthetic polymer that stimulates your body's natural collagen production. Unlike traditional fillers that add immediate volume, PLLA works gradually beneath the skin to restore firmness, reduce wrinkles, and create natural-looking rejuvenation that lasts up to 2+ years.
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Results develop gradually over 2-4 weeks as your body produces new collagen. Full effects are typically visible within 2-3 months. Most patients need 2-3 treatment sessions spaced 4-6 weeks apart for optimal outcomes.
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Yes, PLLA has been used safely in medical applications for over 40 years. It's FDA-approved and requires no allergy testing. Common side effects are mild and temporary: slight redness, swelling, or bruising at injection sites that resolve within 1-2 days.
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TRUESELF® PLLA delivers long-lasting results, typically maintaining tissue remodeling and rejuvenation for 12 to 24 months. Its sustained effect reduces the frequency of follow-up treatments, providing predictable, enduring outcomes for natural, refined facial enhancement.
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TRUESELF® 400 PLLA is ideal for the mid and lower face, including cheeks, temples, jawline, nasolabial folds, neck, décolletage, marionette lines, and chin. It is also effective for volume loss in the décolletage, hands, knees, buttocks, and intimate areas. Not recommended for use in the periocular area around the eyes
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Trueself® offers 100% biocompatible, certified PLLA with a patented, highly effective formula. Maximum quality and proven performance. All vials undergo strict verification, comply with international safety standards, and are available at competitive prices with fast worldwide delivery.
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